MyBioSource.com's ITGAX Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, Immunohistochemistry, and Western Blot. The ITGAX Antibody was generated using ITGAX as the antigen and it reacts with Human, and Rat.
Description
Description: Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis.
Subunit Structure: Heterodimer of an alpha and a beta subunit. Alpha-X associates with beta-2.
Similarity: The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage. Belongs to the integrin alpha chain family